Hepatitis B virus (HBV) | Medchrome

Thirteen HIV / HBV-infected patients (all male, hepatitis B e antigen hepatitis B e antibody positive and negative) were completely absorbed in the village begin Truvada. Were all patients previously exposed to LAM or FTC, and TDF (median 53 months, range 6-123).

  LAM monotherapy patients had prior to September TDF / FTC combination or LAM, were the other six patients exposed to LAM or FTC and TDF combination. The median follow up was 74 weeks (range 16 to 159) and the median decrease was 2.53 HBV (10) log IU / ml (range 1.28 to 7.36). Thirty-eight percent of patients achieved HBV DNA level at the end of the study and eight of 13 (62%) had normal alanine aminotransferase (ALT) with reduction media -28 U / l (range -152 to 37). WAS PTO finished in a patient with renal failure due to toxicity. ETV was tolerated with no change in glomerular filtration rate during the study found.

Hepatitis B virus (HBV) | Medchrome